Issue Date: July 27, 2015 | Web Date: July 23, 2015
Chemists Find A Simple Approach To Activating Amide C–N Bonds
Nature typically outdoes chemists when it comes to efficiently carrying out reactions. But for a nickel—or make that a simple nickel catalyst—a team of UCLA chemists has matched wits with enzymes on cleaving the C–N bond in amides. The achievement overcomes a classic problem of the low reactivity of amides and opens up this key family of compounds to broader use as synthetic building blocks.
Amides are the functional units that link amino acids together . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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