Issue Date: October 26, 2015 | Web Date: October 20, 2015
Understanding Of Bacterial Protein’s Defense Strategy Could Lead To Antibiotics
Bacteria have evolved molecular strategies for regulating the export of toxic metals from their innards. Two independent studies now pinpoint the details of one of these strategies, which protects bacteria from toxic copper concentrations. The work could aid the discovery of antibiotics that target this process to compromise bacterial defenses.
The studies provide complementary structural and mechanistic views that reveal how a transcription factor called CueR activates or represses the gene copA, which encodes the . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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