Volume 94 Issue 23 | p. 7 | News of The Week
Issue Date: June 6, 2016

Virus helps unmask anticancer drug to attack brain tumors

Phase I clinical trial results show promise for new glioma treatment
Department: Science & Technology
News Channels: Biological SCENE
Keywords: analytical chemistry, cancer, drug development, gliomas, brain tumors, 5-fluorouracil, engineered virus

For patients with extremely aggressive brain tumors called high-grade gliomas, treatment options are limited, especially for recurring forms of the disease.

But results from a Phase I clinical trial show promise for a treatment that combines a virus and a prodrug (Sci. Transl. Med. 2016, DOI: 10.1126/scitranslmed.aad9784).

Gliomas exist in two forms in the brain— as a solid tumor and as tumor . . .

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