Volume 94 Issue 29 | pp. 26-30
Issue Date: July 18, 2016

Cover Story

Rapamycin’s secrets unearthed

From its exotic origins to its revival as a potential antiaging compound, rapamycin continues to fascinate
Department: Science & Technology
Keywords: rapamycin, Easter Island, mTOR, cancer, lifespan

On a snowy November day in 1964, a team of about 40 doctors and scientists boarded the Royal Canadian Navy’s H.M.C.S. Cape Scott in Halifax, Nova Scotia. They were headed to Easter Island, a triangle-shaped speck in the South Pacific that’s 2,200 km from its nearest inhabited neighbor. Their goal: to study a group of people—their heredity, environment, and common diseases—who lived in this uniquely remote spot before the Chilean government disrupted their isolation with . . .

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