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Web Date: February 12, 2016

Gene Circuit Boosts High-Temperature Fermentation

Synthetic Biology: E. coli bioengineered to regulate heat stress and cell density are better at producing lysine
Department: Science & Technology
News Channels: Biological SCENE
Keywords: Synthetic biology, Escherichia coli, heat shock proteins, industrial fermentation, lysine, cellular stress

Many of today’s pharmaceuticals, biofuels, and other chemicals are produced by microbial fermentation. But the churning metabolism of bacteria in a bioreactor raises the cells’ temperature, which in turn causes heat stress that hobbles production efficiency. Now, researchers have devised a gene network that boosts the efficiency of Escherichia coli, a workhorse of industrial fermentation, at high temperatures (ACS Synth. Biol. 2016; DOI: . . .

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ISSN 0009-2347
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