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Web Date: March 8, 2016

DNA offers new way to find antibodies and diagnose disease

Super-sensitive method harnesses PCR to detect antibodies in patient samples
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: diagnostics, antibody, PCR

Detecting antibodies as a way to diagnose disease is like trying to find one red ball among thousands of blue ones in a giant swimming pool. In patient samples, the antibodies of interest are few and far between—especially in saliva and urine, and early in the course of a disease. Now, researchers have developed a polymerase chain reaction (PCR) method for detecting antibodies that is 1,000 times as sensitive as enzyme-linked immunosorbent assay (ELISA), the . . .

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Chemical & Engineering News
ISSN 0009-2347
Copyright © American Chemical Society