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Web Date: May 13, 2016

Nanomotors swiftly silence genes

Propelled by sound waves, tiny gold rods pierce cells and promptly deliver siRNA to silence genes
Department: Science & Technology
News Channels: Biological SCENE, Materials SCENE, Nano SCENE
Keywords: nanomedicines, nanomotor, siRNA, gene silencing, nanorod, acoustic, ultrasound, nanowire, cancer, drug delivery

The promise of short interfering RNA (siRNA) is that it can be harnessed to turn off harmful genes in the cell. The difficulty is getting siRNA into the cell in the first place. In a new approach, nanoengineers have driven siRNA into the cell on acoustically-propelled nanomotors, silencing genes faster and more completely than with current methods (ACS Nano 2016, DOI: 10.1021/acsnano.6b01415).

To silence a gene, . . .

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ISSN 0009-2347
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