Volume 95 Issue 18 | p. 10 | Concentrates
Issue Date: May 1, 2017

Multicomponent catalyst promotes multistep reactions

Nanoparticle-on-nanorod material enables four-step reaction in one pot to prepare pharmaceutical intermediates
Department: Science & Technology
News Channels: Organic SCENE, Materials SCENE, Nano SCENE, JACS In C&EN
Keywords: green chemistry, catalysis, tandem reaction, benzoxazole

Brown University chemists have developed a new composite catalyst that can perform four separate reaction steps in sequential order in the same vessel, generating compounds that are useful as intermediates for making antibiotics, anticancer drugs, and other pharmaceuticals (J. Am. Chem. Soc. 2017, DOI: 10.1021/jacs.7b01983). Christopher T. Seto, Shouheng Sun, Chao Yu, and Xuefeng Guo set . . .

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