Volume 95 Issue 2 | p. 9 | Concentrates
Issue Date: January 9, 2017

How HIV inserts DNA into host genomes

Researchers provide first image of machinery used by the virus to integrate its genetic material
Department: Science & Technology
News Channels: Biological SCENE, Analytical SCENE
Keywords: structural biology, intasome, HIV

When HIV infects a host cell, the pathogen converts its RNA code to DNA and then docks the genetic material in a host’s genome. The first glimpse of the HIV machinery that performs this insertion comes courtesy of a team of researchers led by Dmitry Lyumkis at the Salk Institute for Biological Studies (Science 2017, DOI: 10.1126/science.aah5163). Called the . . .

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