Volume 95 Issue 20 | p. 11 | News of The Week
Issue Date: May 15, 2017

Human proteome mapped across the cell

By following more than 12,000 proteins to 30 subcellular compartments, researchers provide a new tool for tracking protein location
Department: Science & Technology
News Channels: Biological SCENE, Analytical SCENE
Keywords: proteomics, human, cell, protein mapping

The places proteins go in the human cell could come into clearer focus thanks to the work of researchers who have tracked 12,003 proteins among 30 subcellular locations where the biomolecules go about their business. A team led by Mathias Uhlén and Emma Lundberg of KTH Royal Institute of Technology examined 22 human cell lines using antibody-based fluorescence microscopy and found that many of the proteins locate in multiple places around the cell (examples in . . .

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