Volume 95 Issue 26 | p. 4 | News of The Week
Issue Date: June 26, 2017

What triggers organ transplant rejection?

Differences in cell receptor between donor and host tissue set rejection in motion, study finds
Department: Science & Technology
Keywords: biological chemistry, immunology, organ transplant, rejection, innate immune system

About half of all transplanted organs get rejected by the body within 10 years. To improve this acceptance rate, researchers want to figure out what triggers the rejection process.

Scientists already know that the adaptive immune system, made up of specialized cells such as B cells, is responsible for recognizing and attacking foreign tissue and invaders. But this system is activated by the less-specialized innate immune system, which is less well understood.

A team led . . .

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