Volume 95 Issue 3 | p. 4 | News of The Week
Issue Date: January 16, 2017 | Web Date: January 12, 2017

Aptamer-based sensors could measure drug levels in real time

General sensor platform makes measurements in awake animals and doesn’t depend on specific target’s chemistry
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: diagnostics, chemical sensing, biomarkers, aptamers, electrochemistry

The few sensors that detect and measure molecules in the body depend on the specific chemistry of the target analyte. For example, glucose sensors quantify levels of the sugar thanks to glucose oxidase, which oxidizes glucose and nothing else.

But what about the vast range of metabolites, drugs, and other molecules that a doctor or patient might want to measure? “What we really want is a generic platform that works in vivo, something that can . . .

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