Volume 95 Issue 31 | pp. 32-38
Issue Date: July 31, 2017

Cover Story

Protein folding: Much more intricate than we thought

Scientists are still uncovering all the players that help keep proteins folded inside cells—and all the ways the process can go wrong
Department: Science & Technology
News Channels: Biological SCENE
Keywords: biochemistry, protein folding, proteostasis, chaperone

When he wasn’t playing the viola or sailing around the Chesapeake Bay during the early 1950s, National Institutes of Health scientist Christian Anfinsen was hard at work in the lab trying to understand proteins on a molecular level. It was during this period that he wrote down a law that every biochemist still has top of mind: The sequence of amino acids in a protein is sufficient to determine its three-dimensional structure.

Life as we . . .

To view the rest of this content, please log in with your ACS ID.



 
Chemical & Engineering News
ISSN 0009-2347
Copyright © American Chemical Society