Volume 95 Issue 32 | p. 6 | News of The Week
Issue Date: August 7, 2017 | Web Date: August 2, 2017

CRISPR corrects mutation in human embryos

Scientists have used the gene-editing tool to fix an error that causes a common heart condition
Department: Science & Technology
Keywords: Biotechnology, CRISPR, genome editing, human embryos, MYBPC3 gene

For the first time in the U.S., researchers have used the CRISPR-Cas9 gene-editing system in human embryos to correct a harmful hereditary gene mutation.

Led by Shoukhrat Mitalipov of Oregon Health & Science University, the team injected eggs from healthy donors with sperm from a donor with hypertrophic cardiomyopathy, a common condition characterized by irregular heartbeat and heart failure. People with the disease carry a mutation in one of two copies of . . .

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