Volume 95 Issue 35 | pp. 34-38
Issue Date: September 4, 2017

Cover Story

A path to the brain’s secrets

Genetic insights and diagnostic tools are helping scientists navigate toward neurological disease treatments
By Chris Morrison, special to C&EN
Department: Business
Keywords: Neuroscience, genetics, biotechnology, CNS

The brain has an earned reputation as a drug development graveyard. Because researchers lacked both a solid understanding of the root causes of neurological disease and good tools to track disease progression or drug effectiveness, our most complex organ long stymied pharmaceutical companies. Over the past decade, many large pharmaceutical makers significantly pared back neuroscience research, and some exited the space entirely.

Those that stayed haven’t yet been rewarded. . . .

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