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Copyright © 2008 American Chemical Society
December 1, 2008 Cover
Volume 86, Issue 48
COVER: Alnylam Pharmaceuticals researchers conductR&D in RNA interference, a strategy for controllinggene expression, at the company�s headquarters site inCambridge, Mass.
Volume 86, Issue 48
PHARMA YEAR IN REVIEW
Drug firms have spent the year adopting new business models aimed at igniting innovation, protecting profitability
COVER: Alnylam Pharmaceuticals researchers conductR&D in RNA interference, a strategy for controllinggene expression, at the company�s headquarters site inCambridge, Mass.
Credit: John Earle
» Full Article
December 1, 2008 Issue
Volume 86, Issue 48
December 1, 2008 Issue, Vol. 86 | Iss. 48
Drug firms have spent the year adopting new business models aimed at igniting innovation, protecting profitability
(pp. 15-24)
Features
Science & Technology
Debate over history of water on the red planet intensifies with new spacecraft data (pp. 59-61)
Cover Story: Measured Metamorphosis
Facing The Giants
Drug companies struggle to deflect generics competition, appease cautious regulators
(pp. 20-21)News of the Week
More Chemical Plants Are Closing
Shrinking economy leads to new layoffs and reductions in capacity
(p.10)Bryostatin, Faster
Highly selective catalysis dramatically reduces steps to multiring structure
(p.11)Climate-Change Talks
Meeting in Poland sets stage for next year's negotiations on new treaty to lower greenhouse gas emissions
(p.11)Departments
Business
New government fund will give $1 billion to promising Chinese drug labs
(pp. 28-29)
Petrochemical makers in Latin America expect to largely escape the global economic downturn
(pp. 30-31)
Two views on how the pharmaceutical industry can best meet the medical needs of impoverished people around the globe
(pp. 33-40)
Drug companies struggle to deflect generics competition, appease cautious regulators
(pp. 20-21)
Drug firms have spent the year adopting new business models aimed at igniting innovation, protecting profitability
(pp. 15-24)Concentrates
(pp. 25-26)
(pp. 25-26)- AstraZeneca, GSK Will Close Plants In Europe
- BASF And Osram Have OLED Prototype
- Altana Snaps Up Clariant Wax Unit
- Showa Denko To Make Pure NH3 In China
- Elevance Strikes Deal With Clemson Spinoff
- Symrise Collaboration Yields Cosmetic Actives
- DuPont Opens R&D Center In India
- Evonik Will Expand Chinese Pharma Plant
- Plastics Museum Closes Its Doors
- Hutchison And Lilly Expand Collaboration
- Sun Buys Chattem For Narcotics Plant
- Alpharma Yields To Takeover By King
- Infinity Strikes Development Deal
- Business Roundup
Government & Policy
Science & Technology
Debate over history of water on the red planet intensifies with new spacecraft data
(pp. 59-61)