Copyright © 2009 American Chemical Society
September 7, 2009 Cover
Volume 87, Issue 36
COVER: A lipid nanoparticle encapsulates strands ofsiRNA for systemic delivery in cells.
Volume 87, Issue 36
RNA INTERFERENCE
Developing drugs based on RNA interference hinges on finding better ways to safely and potently get molecules into cells
COVER: A lipid nanoparticle encapsulates strands ofsiRNA for systemic delivery in cells.
Credit: Illustration by FairmanStudios with permission from Alnylam Pharmaceuticals
» Full Article
September 7, 2009 Issue
Volume 87, Issue 36
September 7, 2009 Issue, Vol. 87 | Iss. 36
Developing drugs based on RNA interference hinges on finding better ways to safely and potently get molecules into cells
(pp. 18-27)
Features
News of the Week
New Approach To A Classic Structure
Oxidative ring-closing reaction boosts yield of key erythromycin precursor
(p.12)Khosla Grows Investment Funds
Cleantech: Venture capitalist has $1 billion to back new technology
(p.13)Crystalline Wiggle Room
Host-Guest Mystery: Trapped molecules hint that crystals may not be as rigid as presumed
(p.14)DNA Nanostructures By Design
DNA Scaffolds: Scientists attain long-sought goal of 3-D DNA crystals
(p.14)Huntsman To Buy Most Of Tronox
Acquisition: Deal will make Huntsman the world’s second largest maker of titanium dioxide
(p.15)Departments
Business
Materials get attention and funding in effort to create U.S. lithium battery industry
(pp. 32-34)
Japanese firm’s plant in Beijing will produce high‑technology water purification membranes
(p.38)Concentrates
(pp. 29-30)
(pp. 29-30)- Merck Sets New Structure
- Clariant Sells Its Silicones Business
- Bayer Wins Agchem Patent Suit In China
- Invista Boosts Stake In Protective Wear
- Wyatt Technology Wins On Appeal
- EU Funds Study Of Nanoparticles
- Archimica And Chemic Partner On APIs
- Roche Takes Option To Buy Lonza Plant
- PTC Will Work With Roche And Celgene
- Shantha Gets Vaccines Contracts
- Catalyst Gets Drug From Northwestern
- Novartis Unveils New Lab Concept
- Trubion, Facet Link For Leukemia Drug
- Business Roundup
ACS News
Government & Policy
How Sotomayor will act on Supreme Court cases affecting the chemical industry can’t be gleaned from her prior rulings
(pp. 42-45)
ACS Meeting News: Department of Homeland Security seeks innovation in antiterrorism technology
(pp. 46-48)
Bayer plans to cut methyl isocyanate use, storage after deadly accident and investigations
(p.50)Books
Education
Gap-year experiences help students recharge and refocus in the classroom
(pp. 92-94)
In a down economy, two-year colleges are a smart choice, but they struggle with overcrowding, scant funding
(pp. 95-96)
Despite a slow start, distance learning is gaining ground in chemistry education
(pp. 97-99)Science & Technology
Developing drugs based on RNA interference hinges on finding better ways to safely and potently get molecules into cells
(pp. 18-27)
ACS Meeting News: Constraining molecules in macrocyclic rings could help address challenges in drug discovery
(pp. 54-57)
Another sudden shortage of technetium‑99m calls for long-term solutions
(pp. 58-64)
ACS Meeting News: New microscopy techniques break the diffraction limit in three dimensions
(pp. 69-71)Concentrates
(p.53)
(p.53)- Recycling Wittig Waste
- Ribozyme's Kick Is In Its Fold
- Neurochemical Net Traps Bad Memories
- Quasi-Intercalation Compounds Boost Battery Performance
- Nanoparticle Array Smells Cancer
- Organic Bioprocess Dominates Oceanic Nitrogen Loss
- Bronze Sculptures Mix Chemistry And Art
- Protein Dimer Hints At Anticancer Target


