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Copyright © 2009 American Chemical Society
November 23, 2009 Cover
Volume 87, Issue 47
COVER: Renaissance of allosteric drugs is fueled byinterest in finding more agents to control G-protein-coupledreceptors (ribbon diagram). Allosteric drugs can finetunea receptor�s signal, much like the radio dials in the19 background.
Volume 87, Issue 47
TUNING THE SIGNAL
Allosteric drugs promise precise control over diseases mediated by G-protein-coupled receptors
COVER: Renaissance of allosteric drugs is fueled byinterest in finding more agents to control G-protein-coupledreceptors (ribbon diagram). Allosteric drugs can finetunea receptor�s signal, much like the radio dials in the19 background.
Credit: Molecule: Science; photo: Shutterstock
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November 23, 2009 Issue
Volume 87, Issue 47
November 23, 2009 Issue, Vol. 87 | Iss. 47
Allosteric drugs promise precise control over diseases mediated by G-protein-coupled receptors
(pp. 12-15)
Features
Business
PharmaMar and Genetrix score in a sector of reticent investors and business-resistant academics (pp. 19-21)
Government & Policy
Once viewed skeptically, plans for intentional intervention in earth’s climate gain traction (pp. 28-30)
Cover Story: The Other Site
News of the Week
Giant Leap For Obstinate Targets
Sugar Chemistry: Parallel combinatorial synthesis yields 12 hard-to-make oligosaccharides
(p.10)Departments
Business
PharmaMar and Genetrix score in a sector of reticent investors and business-resistant academics
(pp. 19-21)
Clean energy legislation threatens industries based on renewable biomass
(pp. 22-23)
Lured by newly affluent consumers, international firms beef up drug manufacturing capabilities in China
(pp. 24-25)Concentrates
(pp. 16-17)
(pp. 16-17)- Genomics Pioneer deCode Goes Bust
- Mitsubishi Chem Bids For Mitsubishi Rayon
- Olin Invests In Railcars For Bleach
- Honeywell To Build UOP Lab In India
- Sasol Mulls Gulf Coast Octene Plant
- Mitsui Chemicals To Raise Capital
- ZeaChem Constructing Cellulosic Biorefinery
- Suntech To Build Its First U.S. Plant
- Porifera Gains Desalination Technology
- GSK Licenses Nabi's Nicotine Vaccine
- Coca-Cola Launching Biobased Bottles
- Merck Cholesterol Drug Takes A Hit
- BUSINESS ROUNDUP
ACS News
Strong trend of rising bachelor’s degrees continues, graduate awards slow
(pp. 38-48)
Government & Policy
Once viewed skeptically, plans for intentional intervention in earth’s climate gain traction
(pp. 28-30)
Science & Technology
Allosteric drugs promise precise control over diseases mediated by G-protein-coupled receptors
(pp. 12-15)
Researchers develop new treatments without fully understanding this common symptom of menopause
(pp. 33-35)