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Copyright © 2010 American Chemical Society
September 27, 2010 Cover
Volume 88, Issue 39
COVER: Laboratory assays such as the Ames test can identify pharmaceutical impurities
Volume 88, Issue 39
PHARMACEUTICALS
Faced with new guidelines that many find constraining, pharmaceutical manufacturers are seeking ways to avoid or reduce harmful contaminants in drugs
COVER: Laboratory assays such as the Ames test can identify pharmaceutical impurities
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September 27, 2010 Issue
Volume 88, Issue 39
September 27, 2010 Issue, Vol. 88 | Iss. 39
Faced with new guidelines that many find constraining, pharmaceutical manufacturers are seeking ways to avoid or reduce harmful contaminants in drugs
(pp. 16-26)
Features
Business
Private equity firms are investing in the risky business of fine and pharmaceutical chemical manufacturing (pp. 32-34)
Education
ACS Meeting News: Technology provides more options, but print textbooks will remain, at least for now (pp. 63-64)
Cover Story: Genotoxic Impurities
Detecting Low-level Impurities
Controlling genotoxic impurities means finding the analytical method best suited to the task
(pp. 27-29)News of the Week
Probing Key Vision Event
Ultrafast Spectroscopy: Rhodopsin isomerization owes speed to conical intersection between electronic states
(p.11)Johnson & Johnson Negotiating To Buy Crucell
Biopharmaceuticals: Acquisition poised to create vaccine franchise for drug conglomerate
(p.12)Science Education Found Wanting
Federal Programs: Presidential advisers seek improved coordination for science and math education
(p.12)Light Controls Surface-Charging
Electrostatics: Method could reveal mechanism of ubiquitous phenomenon behind static cling, copy machines
(p.13)Oil Spill's Size Swells
Deepwater Horizon: Magnitude of gulf accident is far larger than previous estimates
(p.14)Walmart Turns To Thin-Film Solar
Renewable Energy: Project will give Miasolé and First Solar a rooftop tryout
(p.14)Assay For Key Ghrelin Enzyme
Click Chemistry: Approach could help researchers find antiobesity drug leads
(p.15)Departments
Business
Private equity firms are investing in the risky business of fine and pharmaceutical chemical manufacturing
(pp. 32-34)
ACS Meeting News: JAK2 inhibitors show promise at knocking down the symptoms of rare blood cancers
(pp. 36-39)
Green chemistry is touted as a model of industrial and pharmaceutical process efficiency
(p.40)
Controlling genotoxic impurities means finding the analytical method best suited to the task
(pp. 27-29)
Faced with new guidelines that many find constraining, pharmaceutical manufacturers are seeking ways to avoid or reduce harmful contaminants in drugs
(pp. 16-26)Concentrates
(pp. 30-31)
(pp. 30-31)- U.S. Contracts Aim To Boost Medical Emergency Readiness
- Abbott To Cut Jobs After Solvay Deal
- Omnova To Buy Eliokem From AXA
- Evonik Will Sell Carbon Black Business
- Organic Photovoltaics Firm Launched In England
- Bayer Develops Solar Heat Collector
- Dow Advances Wind Energy Materials
- DSM Sells Rubber Business To Teknor
- Trius And Scripps Win Defense Contract
- Eastman Expands 2-Ethylhexanol
- BASF, Solix Join For Chemicals From Algae
- DSM Buys Microbia For Carotenoids
- Novartis Shutters Antibiotic Firm Protez
- Business Roundup
ACS News
Network, interview, and attend workshops online at the ACS Virtual Career Fair
(pp. 70-71)
A laboratory enthusiast from a young age, this ACS Scholar is living his professional dream
(p.69)Awards(p.72)
(p.72)- Alivisatos Wins Pauling Award
- Samuel Lord Is Irving Sigal Fellow
- Doug Turner Named Hammes Lecturer
- Daniel Chiu Wins Young Innovator Award
- Ismar Prize To Robert Griffin
- David Evans Wins Creativity Award
- CORESTA Prize to Rodgman and Perfetti
- Barry Karger Awarded Herovsky Medal
- Ayusman Sen Awarded CRSI Medal
- Robert Becker Is Missouri Teacher Of The Year
- Nominations Sought for Henry Hill Award
- Call For Nominations For Physical Chemistry Awards
- Call For Nominations For Herty Award
- Nominations Open For Remsen Award
Government & Policy
New leadership will examine environmental methods, test alternative recruitment strategies
(pp. 43-45)
Mandatory grant application supplements detailing how data will be shared will increase transparency, agency hopes
(pp. 46-47)Books
A look at how the substances we ingest can affect our brains and behavior
(pp. 65-66)Education
ACS Meeting News: Technology provides more options, but print textbooks will remain, at least for now
(pp. 63-64)
Science & Technology
Organic Chemistry: A surprising cascade reaction is at the heart of the shortest ever route to compound
(p.49)
Water Quality: Silver in our cosmetics and clothes can end up as silver sulfide nanoparticles in sewer sludge
(p.48)
ACS Meeting News: Small molecules that interact with DNA are bound to regulate gene expression
(pp. 50-53)
ACS Meeting News: Interactions between medications, foods, and supplements take many forms
(pp. 55-57)
ACS Meeting News: Process chemists rework synthesis of anti-HIV drug to lower its cost
(pp. 58-59)
Ronald Breslow, a lifelong academic, garners the chemical industry’s big prize, the Perkin Medal
(pp. 60-61)Career & Employment
In an unfavorable pharma job market, many chemists are migrating to new careers
(pp. 75-78)