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Copyright © 2011 American Chemical Society
September 5, 2011 Cover
Volume 89, Issue 36
COVER: Avila Therapeutics’ irreversible inhibitor (red) covalently bonds with a cysteine (yellow) of hepatitis C protease (blue).
Volume 89, Issue 36
Irreversible inhibitors may provide unique benefits in drug development
COVER: Avila Therapeutics’ irreversible inhibitor (red) covalently bonds with a cysteine (yellow) of hepatitis C protease (blue).
Credit: Juswinder Singh & Aravind Prasad/Avila Therapeutics
» Full Article
September 5, 2011 Issue
Volume 89, Issue 36
September 5, 2011 Issue, Vol. 89 | Iss. 36
Irreversible inhibitors may provide unique benefits in drug development
(pp. 19-26)
Features
Business
Custom manufacturers of controlled substances confront unique challenges in a drug market niche (pp. 30-33)
Science & Technology
Alberta’s oil sands are a vast energy resource, but tapping them comes at the expense of a lot of water (pp. 56-59)
Science & Technology
Researchers take cancer-fighting viruses from bench to bedside (pp. 61-62)
News of the Week
Chemists Convene In Denver
ACS Meeting News: ‘Chemistry of Air, Space & Water’ served as meeting theme
(p.11)Pfizer Advances Its Pipeline
Drug Discovery: An approval and key late-stage data restore confidence in the firm’s R&D engine
(p.12)U.S.-Backed Solar Panel Maker Folds
Bankruptcy: Solyndra got loan guarantee but can’t make a profit
(p.12)Making Graphene More Useful
ACS Meeting News: Textbook reaction offers customized modification of carbon material’s properties
(p.13)BioAmber’s Big Bet
Scale-up: Firm expands biobased succinic acid production with plan for facility in Ontario
(p.14)Entrepreneurs Wanted
ACS Meeting News: Task force outlines path to 100,000 new chemistry jobs in 20 years
(p.14)Making Greener Flame Retardants
ACS Meeting News: Environmentally friendly films protect cotton and foam from flames and heat
(p.15)Changeup Yields Indole Alkaloid
ACS Meeting News: Cyclization and nitrene insertion star in synthesis
(p.16)From Dust To Snow
ACS Meeting News: Study of atmospheric dust may herald changes in weather and climate forecasting
(p.16)Departments
Business
Scientific instrument maker vows to stick with the separations and analysis businesses it knows best
(pp. 34-37)
A workhorse for oil and gas extraction sees material advances amid growing demand
(pp. 38-40)
Custom manufacturers of controlled substances confront unique challenges in a drug market niche
(pp. 30-33)Concentrates
(pp. 28-29)
(pp. 28-29)- Chemical Mergers Advance
- Mitsui Changes Route To Isopropyl Alcohol
- Invista Resolves Butanediol Lawsuit
- Lanxess Oxide Helps London See Red
- Evonik Expands Methyl Methacrylate
- Sika Buys Brazilian Adhesives Maker
- UOP Builds Hawaii Biorefinery
- DSM, Sinochem Seal Antibiotics Deal
- Cyalume Purchases JFC Technologies
- Merck Millipore Will Acquire Amnis
- Biogen, Novo Tap Adimab Technology
- Fareva To Buy Pfizer Consumer Goods Plant
- Merck Licenses Zymeworks Process
- Business Roundup
Government & Policy
Bipartisan effort targets overhaul of U.S. patent system
(pp. 44-46)
Agency to investigate accessibility to mentoring programs, potential bias in peer review process
(pp. 47-49)
Yearly gain in carbon dioxide emissions for 2010 tops U.S. GDP growth for first time in more than two decades
(pp. 50-52)Education
Camp helps blind teens study science by tapping into their other senses
(pp. 64-65)
Science & Technology
Alberta’s oil sands are a vast energy resource, but tapping them comes at the expense of a lot of water
(pp. 56-59)
Irreversible inhibitors may provide unique benefits in drug development
(pp. 19-26)
Researchers take cancer-fighting viruses from bench to bedside
(pp. 61-62)Concentrates(pp. 54-55)
(pp. 54-55)- Chemists Build Biobased Resins From Vegetable Oil
- Chromatographic Method Purifies Complex Magnetic Nanostructures
- Isotope Ratio Analysis Traces Feedstock Fingerprints In Drug Syntheses
- Nitric Oxide-Emitting Nanomaterials Kill Microbes
- Hydrophobically Modified Chitosan Latches Onto Blood Cells And Assembles Them Into A Gel
- Metal Nanoparticles Can Be Used As Universal Probe For Many Imaging Methods
- Understanding Oil- Paint Brittleness
- Polymers Shepherd RNA Drugs
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