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ACS Executive Director and CEO Madeleine Jacobs will retire at the end of 2014. Full story.
Copyright © 2011 American Chemical Society
March 21, 2011 Cover
Volume 89, Issue 12
COVER: Shutterstock/C&EN
Volume 89, Issue 12
PHARMACEUTICAL OUTSOURCING
Successful chemistry outsourcing service providers bring an intellectual contribution to the projects they carry out for their drug company partners
COVER: Shutterstock/C&EN
Credit: Shutterstock/C&EN
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March 21, 2011 Issue
Volume 89, Issue 12
March 21, 2011 Issue, Vol. 89 | Iss. 12
Successful chemistry outsourcing service providers bring an intellectual contribution to the projects they carry out for their drug company partners
(p.15)
Features
Government & Policy
Supporters of modern facility to study animal‑borne pathogens still prevail (pp. 32-35)
Science & Technology
Inspired by nature, scientists build walking molecules that stay on track (pp. 43-45)
Cover Story: Pharma Outsourcing
Giving New Life To An Old Molecule
Case study #1: Novasep helps Provepharm quickly scale up to make a better pharmaceutical ingredient
(pp. 16-17)Betting On Boron
Case study #2: Naeja helps Anacor realize its goal of boron-containing pharmaceuticals
(pp. 18-19)Rethinking A Renin Inhibitor
Case study #3: Vitae turns to Solvias for a new synthetic route as well as Phase II clinical production
(pp. 20-21)News of the Week
Japan Fights For Its Rising Sun
Natural Disaster: Frontline reports from the country's chemical enterprise underscore the scope of the tragedy, hopes for recovery
(pp. 8-9)'Good' Cholesterol Comes Into Focus
Heart Disease: Cross-linking mass spectrometry gives clues to native structure of high-density lipoprotein
(p.10)Upbeat Outlook At Pittcon
Instrumentation: Firms expand offerings as consolidation trend continues
(p.10)Berkshire Hathaway To Buy Lubrizol
Dealmaking: Warren Buffett's holding company takes a shine to chemicals
(p.11)Stopgap Redux
Another temporary spending measure will keep the federal government funded until April 8
(p.11)A New Heartbeat Helper
Drug Discovery: Small molecule powers cardiac myosin to counteract heart failure
(p.12)Sperm’s Come-hither Channel
Reproductive Biology: Membrane protein relays steroid hormone signal
(p.12)Departments
Business
French firm’s integration of two manufacturing sites in China should boost competitiveness
(pp. 24-25)
Instrument maker develops near‑infrared analyzers to monitor mined ores
(pp. 26-27)
The UCSF Vice Dean believes universities need to be more active in finding creative partnerships with big pharma
(p.28)
Case study #1: Novasep helps Provepharm quickly scale up to make a better pharmaceutical ingredient
(pp. 16-17)
Case study #2: Naeja helps Anacor realize its goal of boron-containing pharmaceuticals
(pp. 18-19)
Case study #3: Vitae turns to Solvias for a new synthetic route as well as Phase II clinical production
(pp. 20-21)
Successful chemistry outsourcing service providers bring an intellectual contribution to the projects they carry out for their drug company partners
(p.15)Concentrates
(pp. 22-23)
(pp. 22-23)- Pfizer May Cut Back to Core
- Pepsi To Launch Biobased Bottle
- Wacker Will Expand Silicon In Germany
- Cabot Plans Global Carbon Black Boost
- Bayer To Add MDI Capacity In Germany
- Tate & Lyle To Make BDO For Genomatica
- Solazyme Files For $100 Million IPO
- Amgen Will Acquire Pfizer Plant In Ireland
- Tekmira Sues Alnylam Over Technology
- Materia Will Build Plant In Singapore
- Germany’s CABB Gets New Private Owner
- Alphora Invests In Canadian Facility
- Novartis Plans Cuts At Big British Site
- Business Roundup
ACS News
Awards(pp. 58-60)
(pp. 58-60)- 2010–11 Project SEED College Scholarships
- Edinburgh Medal to Carl Djerassi
- Science Mentors Receive Presidential Awards
- Nichols Medal Seeks Nominations
- King Faisal Prize to Whitesides and Zare
- 2011 CINF Scholarship for Scientific Excellence Sponsored by FIZ Chemie Berlin
- Call for Nominations for Young Innovator Award
- Mosher Award To Tobin Marks
- Victor Snieckus Named Laureate Of Lithuania
Government & Policy
President’s fiscal 2012 budget provides great opportunities, even as 2011 budget remains uncertain
(pp. 39-40)
Supporters of modern facility to study animal‑borne pathogens still prevail
(pp. 32-35)
Regulation of chemicals is increasingly being done outside the federal government
(pp. 36-38)Education
For Ph.D. students, organizing symposia for ACS national meetings cultivates workplace skills, opens doors
(pp. 54-55)
Science & Technology
Chemical Analysis: A lightweight and inexpensive instrument uses wire from a light bulb and power from a car battery
(p.41)
Materials Science: Researchers produce an all-carbon composite solar cell from organic components suspended in water
(p.41)
Inspired by nature, scientists build walking molecules that stay on track
(pp. 43-45)
Lone protein’s locale explains distinctive sting
(pp. 46-47)
Decades-long question about Antifungal Agent’s Mechanism is answered
(p.51)
Study provides real-time glimpse of assembly of single spliceosomes
(p.32)Career & Employment
In the wake of the recession, west coast chemists find jobs in recuperating businesses and emerging fields
(pp. 63-66)Newscripts
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