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Copyright © 2012 American Chemical Society
October 1, 2012 Cover
Volume 90, Issue 40
Volume 90, Issue 40
Finding new uses for approved drugs and shelved drug candidates is gaining steam as a pharmaceutical development strategy
Credit: C&EN/Shutterstock
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October 1, 2012 Issue
Volume 90, Issue 40
October 1, 2012 Issue, Vol. 90 | Iss. 40
Finding new uses for approved drugs and shelved drug candidates is gaining steam as a pharmaceutical development strategy
(pp. 15-25)
Features
Business
European fine chemicals producers adapt big pharma factories to perform contract manufacturing work (pp. 34-37)
Science & Technology
In covalent mechanochemistry, chemists are discovering new reactivity by subjecting molecules to mechanical force (pp. 55-57)
News of the Week
Implantable Silicon Devices Designed To Disappear
Nanotechnology: Researchers construct ultrathin silicon electronics to dissolve harmlessly at end of useful lifetime
(p.9)Congress Remains Divided To The End
Election Recess: Partisan battles shift from Capitol Hill to campaigns
(p.10)Economic Recovery Is Slow, Chemical Industry Trade Group Indicator Finds
U.S. Economy: Leading chemistry indicator points to stunted growth
(p.10)Congress Averts Federal Budget Crisis
Budget: House and Senate pass measure to keep U.S. government funded through late March
(p.11)Syngenta, Bayer CropScience, and BASF Spend Big On Biological Pest Control And Agricultural R&D
Agriculture: Companies expand arsenal of pesticides and seeds
(p.11)Bacteria Emit Chemical Stews
Natural Products: Researchers detect myriad new compounds, insect pheromones
(p.12)Russian Chemist Released From Jail
Criminal Justice: Supporters say Olga Zelenina was unjustly behind bars for giving expert scientific opinion
(p.12)Sanofi’s R&D Revamp Detailed?
French pharma firm to cut 900 jobs in France but keep most research sites open
(p.13)Source Of Nitrogenase’s Carbide Found
Enzymology: Mysterious origin of carbide in nitrogen-fixing enzyme has been found
(p.13)Departments
Business
The big pharma firm is banking on proximity to breed teamwork and ultimately improve the outcome of early-stage R&D
(pp. 28-32)
Debate over the science of estrogenic activity in plastics heads to a Texas court
(pp. 40-41)
Versalis opens an office in the country as part of a bid to reduce reliance on Europe
(pp. 38-39)
Finding new uses for approved drugs and shelved drug candidates is gaining steam as a pharmaceutical development strategy
(pp. 15-25)
European fine chemicals producers adapt big pharma factories to perform contract manufacturing work
(pp. 34-37)Concentrates
(pp. 26-27)
(pp. 26-27)- Popcorn Lung Sufferer Gets $7 Million Award
- Chemtura To Enlarge India Bromine Assets
- Wacker Expands In South Korea
- Arsenal Capital Buys IGM Resins
- Gevo Stops Isobutyl Alcohol Production
- Evonik To Build MMA Facility In U.S.
- Linde Purchases Chinese Gas Unit
- BASF Opens U.S. Dermatology Lab
- Novo Nordisk Boosts Beijing R&D
- Roche Picks New East Coast Hub
- Firms, Nonprofits Join For TB, Cancer R&D
- MacroGenics, Servier Form Antibody Pact
- Bristol-Myers And Vanderbilt Team Up
- Business Roundup
ACS News
Government & Policy
Lawmakers question surge in use of special hiring authority by HHS, EPA
(pp. 48-49)
Panel calls for changes to improve confidence in federal scientific advisory boards and research reviews
(p.51)
Time slips by as U.S. continues impasse over fate of spent fuel, radioactive nuclear waste
(pp. 44-46)Education
Initiative encourages faster uptake of green chemistry and toxicology in the undergraduate curriculum
(pp. 64-65)
Science & Technology
As DNA sequencing costs drop, scientists begin cataloging plants’ beneficial band of microbial stowaways
(pp. 62-63)
Scientists celebrate the centennial of a reaction that makes cooked food tasty, but also produces worrisome molecules in our meals and bodies
(pp. 58-60)
Sci-fi thriller provides a thought-provoking commentary on technology and time travel
Web Exclusive
In covalent mechanochemistry, chemists are discovering new reactivity by subjecting molecules to mechanical force
(pp. 55-57)