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Copyright © 2012 American Chemical Society
November 12, 2012 Cover
Volume 90, Issue 46
Volume 90, Issue 46
Chemistry and biology have merged with high-powered statistical analysis in drug discovery labs
Credit: AstraZeneca
» Full Article
November 12, 2012 Issue
Volume 90, Issue 46
November 12, 2012 Issue, Vol. 90 | Iss. 46
Chemistry and biology have merged with high-powered statistical analysis in drug discovery labs
(pp. 11-14)
Features
Business
Chemical firms outline restructurings and layoffs, as they report ongoing weakness in earnings (pp. 18-20)
Science & Technology
Public participation in chemical research drives discoveries in solar fuels, environmental health, and more (pp. 30-32)
News of the Week
Obama Wins, Congress Remains Split
Elections: U.S. votes to keep status quo, politicians promise bipartisanship
(p.5)A Big Bet On Nitrogen Fertilizer
Agriculture: CF Industries will plow $3.8 billion into U.S. facilities to make ammonia and related products from natural gas
(p.6)Methane-Munching Microbes Reduce Sulfur
Climate: Seafloor archaea couple chemistry to produce zero-valent sulfur
(p.6)Molecular Building Blocks Self-Assemble Into Trefoil Knot
Organic Chemistry: Hydrophobic effect drives spontaneous formation of three-loop knot
(p.7)Ziarco Launches With Pfizer Allergy Assets
Small firm is the latest start-up to emerge from shuttered Sandwich, U.K., site
(p.7)Proteins Made To Order
Design Rules: Principles integrate structure and function from the ground up
(p.8)Chemical Company Sales, Profits Shrink In Japan
Finance: Global slowdown takes toll on major Japanese chemical firms
(p.9)Temperature- Or pH-Guided Protein Self-Assembly
Modifications enable alternative mechanisms that yield distinct sizes
(p.9)Departments
Business
Chemistry and biology have merged with high-powered statistical analysis in drug discovery labs
(pp. 11-14)
Most major firms continue to see declining sales and earnings
(pp. 21-22)
New Bayer biologics head tells how he lost his job, joined a start-up firm, and sold it to Bayer for $500 million
(p.23)
Chemical firms outline restructurings and layoffs, as they report ongoing weakness in earnings
(pp. 18-20)Concentrates
(pp. 16-17)
(pp. 16-17)- U.K. Seeks Science Alliances
- DSM Will Purchase U.S. Nutrition Firm
- Private Equity Firms Raise Bid For TPC
- Wacker Gets Technical In Latin America
- India’s Gulf Oil Acquires Houghton
- BASF Invests And Divests In Europe
- Restart Not In Sight For Shokubai Plant
- BioAmber To Supply Plastics For Autos
- Shin-Etsu Acquires Drug Delivery Firm
- Life Technologies Buys Microscopy Firm
- Brain Drug Firm Envoy Is Going To Takeda
- Lilly Will Expand Insulin Production
- India Busts Another Western Drug Patent
- Business Roundup
ACS News
Complexity of journals’ pricing adds to tension between publishers and customers
(pp. 35-37)
Science & Technology
Public participation in chemical research drives discoveries in solar fuels, environmental health, and more
(pp. 30-32)Concentrates(pp. 28-29)
(pp. 28-29)- Anion To Radical To Polyarene
- Nanorods Tag Tumors For Surgery
- Nanoconfinement Prevents Nickel Catalyst From Fouling
- Missing Xenon Still At Large
- Mass Spec Method Fingerprints Dyed Fibers
- Nanocrystals Make Hydrogen For Days
- Lithium-Air Battery Gets A Safety Boost
- Velcro-Like Protein Both Activates And Tracks Biochemical Targets