March 3, 2014 Issue | Chemical & Engineering News
 
 
 
Copyright © 2014 American Chemical Society
 

March 3, 2014 Issue

Volume 92, Issue 9
09209-cover1-structuresweb
March 3, 2014 Issue, Vol. 92 | Iss. 9
Drug companies turn to contract manufacturers for help in commercializing small-molecule drugs
By Michael McCoy
(p.13)
Features
Government & Policy
Pending bills target specific chemicals but also eye establishment of substances of concern lists (pp. 35-37)
Science & Technology
Max Planck Institute for Coal Research celebrates 100 years (pp. 40-41)
Back Issues
 
Staying On Track
Case Study 1: Ariad and Ash Stevens pursue demanding Quality by Design methods while maintaining a quick pace
(pp. 14-16)
A Mercury Chelator
Case Study 2: PCI brings analytical chemistry to bear on a nutritional supplement headed to clinical trials
(pp. 18-19)
Immediate Results
Case Study 3: Lonza helps Pharmacyclics quickly bring a cancer drug to market
(pp. 20-21)
 

News of the Week

New Route To Improved Heparins

Drug Discovery: Chemoenzymatic analogs may sidestep key problems of current anticoagulants
(p.7)

Informing The Climate Debate

Report: National Academy of Sciences and Royal Society lay out climate-change science for the public
(p.8)

U.S. Chemical Investment Soars

Business: New projects tied to shale gas exceed $100 billion
(p.8)

Peering Inside Reactors

Analytical Chemistry: Microspectroscopy tracks multistep process in action
(p.9)

White House Seeks To Bolster Patent System

Innovation: Administration takes steps to prevent the granting of weak patents, frivolous patent litigation
(p.9)

A Challenging Conjugation

Bioactivity: Linking to antibody fragment enhances immune-system-regulating agent
(p.10)

A Pharma-Friendly Fluorination

Organic Synthesis: Aryl bromide and iodides succumb to Pd-catalyzed reaction
(p.10)

Detecting Citrus Blight

Agriculture: Portable spectrometer identifies signature volatile organic compounds before it’s too late
(p.11)

European Firms Feel The Squeeze

Earnings: Chemical firms struggle to recapture sales, earnings growth
(p.11)
 

Departments

09209-cover3-PCIcxd

Business

Case Study 2: PCI brings analytical chemistry to bear on a nutritional supplement headed to clinical trials
(pp. 18-19)
Case Study 3: Lonza helps Pharmacyclics quickly bring a cancer drug to market
(pp. 20-21)
Case Study 1: Ariad and Ash Stevens pursue demanding Quality by Design methods while maintaining a quick pace
(pp. 14-16)
Drug companies turn to contract manufacturers for help in commercializing small-molecule drugs
(p.13)
Companies are attempting to add plastics-to-oil technology to the waste management arsenal
(pp. 32-33)
Japanese and South Korean producers stir up the market for polyphenylene sulfide plastic
(pp. 28-31)
Biotech firms overcome technical challenges to make fiber stronger than steel and tougher than Kevlar
(pp. 24-27)

Education

With degrees in chemistry, identical triplets are carving out their own careers—in medicine, dentistry, and forensic science
(p.47)
09209-scitech1-OpeningDay1914cxd

Science & Technology

Max Planck Institute for Coal Research celebrates 100 years
(pp. 40-41)
Researchers discover the first case of an insect’s ability to neutralize its enemy’s poison
(pp. 44-45)
New drug prospects target inflammation as research highlights complexity of the condition
(pp. 42-43)

Career & Employment

Editor's Page

Letters

Letters(pp. 4-5)