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Copyright © 2014 American Chemical Society
March 24, 2014 Cover
Volume 92, Issue 12
COVER: This view down the barrel of sodium channel Na
Volume 92, Issue 12
Human genetic studies point drugmakers to a specific sodium channel target for painkillers
COVER: This view down the barrel of sodium channel Na
Credit: Nat. Commun./C&EN
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March 24, 2014 Issue
Volume 92, Issue 12
March 24, 2014 Issue, Vol. 92 | Iss. 12
Human genetic studies point drugmakers to a specific sodium channel target for painkillers
(pp. 10-14)
Features
Government & Policy
President Obama’s 2015 R&D budget request doesn’t keep up with inflation (pp. 26-29)
Science & Technology
In a typical day, process chemists select reagents, pore over synthetic routes, think about safety, and manage costs (pp. 30-33)
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Chemists Convene In Dallas
ACS Meeting News: ‘Chemistry & Materials for Energy’ was national conference’s theme
(p.4)Stem Cell Memories
ACS Meeting News: Growing stem cells in stiff or soft environments influences their future differentiation
(p.5)Trinseo Makes Second Attempt To Go Public
Polymers producer formerly known as Styron files plans to pay down debt
(p.5)ACS Meeting News: Reagent Assembles Ring Motifs Common In Drugs
Method builds medium-sized nitrogen heterocycles with challenging substitution patterns
(p.6)California Targets Products
Regulation: State proposes elimination of certain chemicals or substitution with safer alternatives
(p.6)Certain Pet Flea Collars’ Days Are Numbered
EPA, two manufacturers agree to phase out products that contain propoxur, a neurotoxin
(p.7)Role Of Folded DNA Revealed
ACS Meeting News: Study shows i-motifs and related hairpins activate or repress gene expression
(p.7)Prenatal Vitamin A Essential For Offspring Immune Health
Reproductive Medicine: A healthy fetal immune system in mice depends on mothers ingesting the vitamin
(p.8)FDA Bans Another Indian Drug Plant
Generics: Quality problems plague Indian producers
(p.9)Spray-On Polymer Mats Seal Surgical Incisions
Biomaterials: Researchers apply mats of biodegradable nanofibers directly onto tissues using a commercial airbrush
(p.9)Departments
Business
Eli Lilly & Co. tries to get creative about cultivating compounds that might otherwise collect dust
(pp. 22-23)
Natural gas, funding concerns shadowed technologies that promise low- or no-carbon energy
(p.24)
Pressured by high costs and a shrinking home market, producers are getting serious about slashing unprofitable businesses
(pp. 18-20)Concentrates
(pp. 16-17)
(pp. 16-17)- Wacker Eyes U.S. Expansion
- Dow Earmarks More Units For Sale
- Tedlar Covers Goodyear Blimp
- KiOR In Desperate Financial Straits
- Evonik Sets Facility For Novel Methionine
- LG Chem Buys U.S. Filtration Firm
- Air Liquide Spends On R&D In France
- Sensient Slugs Back At Activist Investors
- BMS Inks Deal With Five Prime
- Biogen, Atlas Give Ataxion Booster Shot
- Thermo Fisher Buys Prionics
- MedImmune Adds Two Academic Partners
- Japanese Drug Firms To Share Compounds
- Business Roundup
ACS News
What you didn’t learn in graduate school about being a professor
(p.36)
Government & Policy
President Obama’s 2015 R&D budget request doesn’t keep up with inflation
(pp. 26-29)
Science & Technology
Human genetic studies point drugmakers to a specific sodium channel target for painkillers
(pp. 10-14)
Biosynthetic protein may steer a reaction after the transition state to home in on a single natural product
(pp. 34-35)
In a typical day, process chemists select reagents, pore over synthetic routes, think about safety, and manage costs
(pp. 30-33)Concentrates(pp. 28-29)
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- Building Tissue Layer By Layer
- Papermaking Waste Could Fix BPA Problem
- Teaching Zinc A New Trick
- Drug Delivery System May Treat Common Cattle Infection
- Lactone Helps Push Carbon Dioxide To Couple With Olefins
- Gut Microbes Bring Out Best In Cocoa
- For Drug Analysis, Paper Spray MS Is Faster Than LC/MS
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