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Copyright © 2015 American Chemical Society
September 7, 2015 Cover
Volume 93, Issue 35
COVER: Structure of the Cas9 complex depicts the Cas9 enzyme (gray, white), along with guide RNA (green-yellow), and target DNA (red). Blue dots mark positions where Cas9 cuts the DNA.
Volume 93, Issue 35
Rapid adoption of CRISPR/Cas9 technology is changing our ability to explore genomics and treat genetic diseases
COVER: Structure of the Cas9 complex depicts the Cas9 enzyme (gray, white), along with guide RNA (green-yellow), and target DNA (red). Blue dots mark positions where Cas9 cuts the DNA.
Credit: Ian Slaymaker and Lauren Solomon/Courtesy of the Broad Institute
» Full Article
September 7, 2015 Issue
Volume 93, Issue 35
September 7, 2015 Issue, Vol. 93 | Iss. 35
Rapid adoption of CRISPR/Cas9 technology is changing our ability to explore genomics and treat genetic diseases
(pp. 14-20)
Features
Science & Technology
Researchers develop antiprion compounds that disrupt protein aggregation in animal brains (pp. 37-39)
News of the Week
First Metal-Organic Framework Made With Protein
Bioinorganic Chemistry: Engineered protein, metal ion, and linker form new type of hybrid material
(p.9)Chemical Safety Board Gets New Chief
Reform: Sutherland calls for internal examination at struggling panel
(p.10)China Seeks Factory Relocations In Wake Of Tianjin Disaster
Fallout: As another chemical facility explodes, authorities in Beijing ponder response
(p.10)Another Neurodegenerative Disease Linked To Prion Mechanism
Neuroscience: α-Synuclein acts like a prion protein and can transmit Parkinson’s-like disease to mice
(p.11)Environmental Protection Agency Proposes To Halt Health Care Facilities From Flushing Some Drugs Down The Drain
Water Pollution: Action aimed at unused pharmaceuticals considered hazardous waste
(p.11)Textiles Are New Growth Business For Chemical Firms
Manufacturing: Once declining market shows new signs of life in the U.S.
(p.12)Wasp Venom Peptide Selectively Punctures Cancer Cell Membranes
Drug Discovery: Peptide may target phospholipids when attacking tumor cells
(p.12)Mutant Enzyme Helps Plants Tolerate TNT
Environment: Plants with mutant gene thrive in TNT-laden soil
(p.13)Probe Molecules Detect Formaldehyde In Live Cells
Chemical Biology: Two different probes undergo aza-Cope reactions after binding the metabolite
(p.13)Departments
Business
After decades of searching, Mexico’s petrochemical industry may finally have found a formula for success
(pp. 25-27)
Normally sensitive about its image, China lets information flow after deadly explosion
(p.28)
Rapid adoption of CRISPR/Cas9 technology is changing our ability to explore genomics and treat genetic diseases
(pp. 14-20)Concentrates
(pp. 21-22)
(pp. 21-22)- Ajinomoto Will Exit European Sweeteners
- Nova Scores Patent Win In Dow Case
- Bayer Hives Off Covestro Business
- Lithium Suppliers Plan For Growth
- BASF Hits The Road With Schwalbe
- Givaudan Acquires Cosmetic Actives Firm
- France’s Fareva Buys Merck API Plant
- Regis Hits Switch On Potent Compounds
- Sanofi And Google Join Against Diabetes
- Novo Nordisk Nabs Diabetes Start-ups …
- … And Invests In Diabetes Drug Actives
- Amicus Buys Rare Disease Firm Scioderm
- BMS Gets Rights To Promedior Drug
- Business Roundup
ACS News
Snapshots from the American Chemical Society national meeting
(p.48)
The two-century-old kaliapparat found on the ACS logo is a remarkably precise device for measuring carbon content
(pp. 46-47)
Government & Policy
Irreproducible research costs the U.S. billions, new analysis shows
(p.31)
Science & Technology
ACS Meeting News: Encoding DNA with digital information and encasing it in silica nanoparticles could save documents and data for future generations
(pp. 40-41)
ACS Meeting News: Princeton team of chemists is using visible-light-activated catalysts to make difficult reactions possible
(pp. 42-43)
Researchers develop antiprion compounds that disrupt protein aggregation in animal brains
(pp. 37-39)Concentrates(pp. 32-33)
(pp. 32-33)- DNA-Programmed Synthesis Of Tissues
- New Class Of Protein-DNA Nanostructures
- Antibody Treats Rare Bone Disorder In Mice
- Materials: Spinning weaves large and small graphene platelets into aligned fibers with excellent properties
- A Little Palladium Does A Lot Of Cross-Coupling
- Beating Chronic Myeloid Leukemia
- Missing Piece Of Catalysis Puzzle Found
- DNA ‘Yarn Balls’ Deliver Biomolecules
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