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Copyright © 2016 American Chemical Society
July 4, 2016 Cover
Volume 94, Issue 27
Volume 94, Issue 27
Drugmakers juggle isotopes in hopes of achieving novelty, stability, and success
Credit: Richard C. Smith
» Full Article
July 4, 2016 Issue
Volume 94, Issue 27
July 4, 2016 Issue, Vol. 94 | Iss. 27
Drugmakers juggle isotopes in hopes of achieving novelty, stability, and success
(pp. 32-36)
Features
Government & Policy
Congress gives agency more authority to regulate health and environmental risks and demand toxicity data (pp. 18-20)
Science & Technology
Chemists gather at annual conference to assess advancement in pollution-prevention strategies (pp. 22-25)
News of the Week
U.K. chemistry enterprise feels ‘Brexit’ pain
U.K. scientists and chemistry-based companies brace for a period of trouble and uncertainty
(p.5)Antarctic ozone hole shows signs of repair
New study documents increase in O3 levels for the first time
(p.7)Patent royalties suit against Harvard settled
Details of the agreement between former grad student Mark Charest and the school are undisclosed
(p.7)Asymmetric difluorination of alkenes achieved
Challenging reaction efficiently generates sought-after chiral difluoromethyl groups
(p.8)How spongy silicon could open new doors in bioelectronics
New form of silicon boosts element’s biocompatibility and activates neurons with an assist from light
(p.8)Structure of Ebola virus’s glycoprotein reveals an Achilles heel
Drug designers may want to target a region that destabilizes the pathogen’s infection machinery
(p.9)Tiny peptide targets brain injuries
Molecule could help researchers deliver therapeutics for traumatic brain injury
(p.9)New method used to discover potential helium source
Technique could alleviate recurrent shortages of the noble element, used in scientific instruments
(p.12)Three materials start-ups attract funding
Firms say their technology will improve performance of solar cells, batteries, and 3-D printed parts
(p.12)Dow to lay off 2,500 in wake of Dow Corning purchase
The company is also closing two plants in effort to reach $400 million in savings
(p.13)Modern Meadow, developer of lab-grown leather, raises $40 million
The start-up will use the funds to scale up their process, which derives collagen from modified cells
(p.13)Pfizer goes to China for biologic drugs
Planned $350 million facility will employ single-use bioreactors from GE
(p.13)National Academy says proposed human subjects regulation should be scrapped
Panel recommends different take on Common Rule
(p.15)Glyphosate temporarily allowed in EU
Controversial herbicide reauthorized until end of 2017
(p.16)Departments
Business
Recent surveys show success rates are tied to modality and disease area
(pp. 26-27)Concentrates
(pp. 14-15)
(pp. 14-15)- Universal beefs up OLEDs
- SABIC, Aramco study oil-to-chemicals
- Covestro plunges into 3-D printing
- FTC challenge scuttles merger…
- … As Air Liquide sells operations to Matheson
- Amyris inks scent, technology deals
- Encapsulation firm buys itaconic acid maker
- Icagen to acquire Sanofi R&D site
- Moderna wins big Merck investment
- Sanofi, Boehringer agree to swap assets
- Merck to clean up vaccines
- Two university spin-offs emerge
- Business Roundup
Government & Policy
Congress gives agency more authority to regulate health and environmental risks and demand toxicity data
(pp. 18-20)
Science & Technology
Chemists gather at annual conference to assess advancement in pollution-prevention strategies
(pp. 22-25)
Drugmakers juggle isotopes in hopes of achieving novelty, stability, and success
(pp. 32-36)
Geochemist and marathoner Elizabeth Herndon says finding the perfect work-life balance is a balancing act unto itself
(pp. 30-31)
Un nuevo estudio muestra por primera vez un aumento en los niveles de ozono
(p.7)Career & Employment
Children’s Tumor Foundation vice president for R&D leaves behind music for a medicinal chemistry career
(p.28)Newscripts
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