Copyright © 2017 American Chemical Society
 

March 13, 2017 Issue

Volume 95, Issue 11
09511-cover-pack
March 13, 2017 Issue, Vol. 95 | Iss. 11
Three stories of creating new therapeutic molecules
By Michael McCoy
(pp. 36-45)
Features
Science & Technology
While Trump takes aim at immigration, foreign trainees consider taking their talents elsewhere (pp. 20-21)
Science & Technology
C&EN’s curated list of places to go, people to see, and science to learn (pp. 32-33)
Back Issues
 

News of the Week

Dual therapy first weakens, then kills antibiotic-resistant pathogens

The drug pentamidine disrupts the outer membrane of Gram-negative bacteria, allowing antibiotics inside to finish the job
(p.5)

George Olah dies at age 89

Chemistry Nobel Laureate advanced carbocation chemistry and championed alternative energy technology
(p.6)

Quantum effect could explain how chiral molecules interact

Electron spin polarization promotes recognition between molecules of similar chirality
(p.6)

Magnetic data bit stored on single atom

Scanning probe study achieves ultimate in data-storage miniaturization
(p.7)

Enzyme-inspired route to heterocycle functionalization

Bifunctional metal agents reversibly coordinate heterocycles and derivatize them at remote sites
(p.8)

Fractious fractions teased from crude oil

Separation method corrals key compounds to improve petrochemical processing and pollution assessment
(p.9)

Nestlé, Danone look to renewable bottles

The companies hope to crack the biobased polyester problem by working with start-up Origin Materials
(p.12)

Rejecting PPG bid, AkzoNobel will exit chemicals

Proposed merger is latest consolidation move for industry
(p.12)

DSM, Evonik form omega-3 joint venture

Partners will build $200 million plant in U.S. to meet demand in fish and pet foods
(p.13)

Instrument makers invest in cloud computing

Thermo Fisher, Waters, and others emphasize informatics at Pittcon conference
(p.13)

Vertex buys Concert’s cystic fibrosis drug

Acquisition validates deuterated drug design and expands firm’s position in disease area
(p.13)

EPA scraps methane reporting for oil and gas industries

Pruitt kills data collection at request of several states
(p.16)
 

Departments

Print

Business

Individual company results were mixed as major products were beset by patent squabbles and expirations
(pp. 28-29)
Demand was strong for some specialties, but results showed the impact of slow growth and lower prices
(pp. 26-27)
Biopesticide maker Vestaron says fruit and vegetable farmers are ready for its novel pest chemistry
(pp. 30-31)
Three stories of creating new therapeutic molecules
(pp. 36-45)
The companies hope to crack the biobased polyester problem by working with start-up Origin Materials
(p.12)

ACS News

San Francisco, April 2–6
(p.49)
09511-scitech4-interviewcxd

Science & Technology

Northwestern professor discusses his chemistry legacy and hopes for scientists in China
(pp. 34-35)
While Trump takes aim at immigration, foreign trainees consider taking their talents elsewhere
(pp. 20-21)
Using electric current as a reagent streamlines reactions by avoiding hazardous reagents, generating less waste, and reducing cost
(pp. 23-25)
C&EN’s curated list of places to go, people to see, and science to learn
(pp. 32-33)
El fármaco pentamidina inhabilita la membrana externa de las bacterias gramnegativas, permitiendo que los antibióticos entren en la célula y hagan su trabajo.
(p.5)
Selections from cen.chempics.org, where C&EN showcases the beauty of chemistry
(p.16)

Editor's Page