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Accelerating Drug Discovery Using Micro-Flow LC/MS
Thursday, May 10, 2012
USA 11:00 a.m. EDT / 10:00 a.m. CDT / 8:00 a.m. PDT / 15:00 GMT
Speakers
Robert Turner, Ph.D.
Principal Scientist,
Applied Markets, CoMentis
Analytical Biochemistry
Tina Settineri, Ph.D.
Director, HPLC Products,
Eksigent, part of AB SCIEX
Moderator
Celia Arnaud
Senior Editor
C&EN
In these presentations, the use of microflow UHPLC using 0.5 mm ID and 1.0 mm ID columns will be described as an innovative method to accelerate bioanalytical drug discovery by dramatically increasing throughput and decreasing method development time relative to traditional higher flow UHPLC systems utilizing 2.1 mm ID columns. Numerous examples from quantitative analyses of In-Vitro ADME characterization will be presented as well as bioanalysis of In-Vivo samples for late stage discovery profiling and validation. Added benefits for reduced sample size requirements and reduced cost of ownership will also be discussed.
Who should attend?
People interested in the following should attend:
• Mass Spectrometry
• Bioanalytical Drug Discovery
• Micro LC, Ultra LC
• ADME
