Automated Zeta Potential to Characterize the Charge for Proteins and Particles
 
 
CEN Webinars: Stronger Bonds

Automated Zeta Potential to Characterize
the Charge for Proteins and Particles

 

Tuesday, May 22, 2012

USA 11:00 a.m. EDT / 10:00 a.m. CDT / 8:00 a.m. PDT / 15:00 GMT

 

Who should attend?


• Scientists interested in characterizing macromolecular or particle charge in solution.

• Researchers who wish to automate mobility measurements and increase the throughput of their research and experiments.

• Researchers who wish to measure electrophoretic mobility of samples with high conductivities.

• Formulation scientists.

• Researchers who want to learn about a state-of-the-art analytical technique for efficiently characterizing proteins, particles and polymers in solution.

Speaker


Dr. Vincent Hsieh, Ph.D.,
Senior R&D Scientist,
Wyatt Technology
Corporation


Moderator


Elizabeth K. Wilson
Senior Editor
C&EN
 


This webinar will present a few of the latest developments associated with electrophoretic mobility measurement techniques. The emphasis will be placed on three recent milestones in this measurement technique including:

• Breakthroughs in detection sensitivity.

• Zeta-potential measurements that can be automated using a common autosampler.

• The ability to measure samples in highly saline solutions where electrolysis previously rendered the measurements impossible to make.

During the webinar, we will show how zeta-potential measurements can be automated for unattended acquisition of mobility and size data. The eternal issue of the electrolysis problem faced by researchers while characterizing samples in high-salt solutions has been resolved and will be discussed. Now samples with high conductivities (near or above physiological saline) can be measured.

What Participants Will Learn:


• Principles of mobility measurements: what is phase-analysis light scattering (PALS), and how it has evolved into multiple angle PALS.

• How biomolecules can be measured without denaturing them.

• How zeta potential instruments can be combined with an HPLC pump and autosampler to enable high-throughput, unattended measurement of electrophoretic mobility and hydrodynamic radius.

• How zeta potential instruments can be combined with an HPLC pump and autosampler to enable high-throughput, unattended measurement of electrophoretic mobility and hydrodynamic radius.

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Sponsored by:

Register FREE at http://tinyurl.com/dx9uh7e