Characterizing Solution Properties of Biopharmaceuticals
Using Light Scattering Combined with Orthogonal Analytical Approaches
Thursday, October 4, 2012
USA 11:00 a.m. EDT / 10:00 a.m. CDT / 8:00 a.m. PDT / 16:00 GMT
Who should attend?
Scientists and managers who are involved in biopolymer (protein) analysis who must use orthogonal methods of characterization
Michelle Chen, Ph.D.
Director of Analytical Services
Wyatt Technology Corporation
Comprehensive characterization using orthogonal analytical techniques for biopharmaceuticals, including biosimilars, is essential in ensuring product quality and safety. This webinar will focus on some important analytical techniques which, when combined with multiple-angle light scattering (MALS) and dynamic light scattering (DLS) detection, provide complimentary insights in characterizing biological products in solution. The benefits, limitation, and applications of size exclusion chromatography (SEC)-MALS, field flow fractionation (FFF)-MALS, as well as batch MALS and DLS method will be discussed.
What Participants Will Learn:
• The pros and cons of size exclusion chromatography (SEC) and field flow fractionation (FFF) analysis.
• The pros and cons of batch dynamic light scattering (DLS) and multi- angle light scattering (MALS).
• The benefits of adding MALS to SEC and FFF analysis.
• The benefits of orthogonal analysis with SEC, FFF, and batch LS analysis.