Characterizing Solution Properties of Biopharmaceuticals<br /> Using Light Scattering Combined with Orthogonal Analytical Approaches
 
 
CEN Webinars: Stronger Bonds

Characterizing Solution Properties of Biopharmaceuticals
Using Light Scattering Combined with Orthogonal Analytical Approaches

 

Thursday, October 4, 2012

USA 11:00 a.m. EDT / 10:00 a.m. CDT / 8:00 a.m. PDT / 16:00 GMT

 

Who should attend?


Scientists and managers who are involved in biopolymer (protein) analysis who must use orthogonal methods of characterization

Speaker


Michelle Chen, Ph.D.
Director of Analytical Services
Wyatt Technology Corporation


Moderator


Stu Borman
Senior Correspondent
C&EN
 


Overview:


Comprehensive characterization using orthogonal analytical techniques for biopharmaceuticals, including biosimilars, is essential in ensuring product quality and safety. This webinar will focus on some important analytical techniques which, when combined with multiple-angle light scattering (MALS) and dynamic light scattering (DLS) detection, provide complimentary insights in characterizing biological products in solution. The benefits, limitation, and applications of size exclusion chromatography (SEC)-MALS, field flow fractionation (FFF)-MALS, as well as batch MALS and DLS method will be discussed.

What Participants Will Learn:


• The pros and cons of size exclusion chromatography (SEC) and field flow fractionation (FFF) analysis.

• The pros and cons of batch dynamic light scattering (DLS) and multi- angle light scattering (MALS).

• The benefits of adding MALS to SEC and FFF analysis.

• The benefits of orthogonal analysis with SEC, FFF, and batch LS analysis.

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