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Organic SCENE

An up-to-the-minute stream of news about organic chemistry, including coverage of synthesis, reaction mechanisms, catalysis, medicinal chemistry, natural products, and organic polymers.

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August 25, 2014

Methyl Geometry Explains Aspirin Polymorph Stability

Computational study suggests better coupling of electronic and lattice motion reduces energy to favor one crystal form over another

August 25, 2014

Chemists Stabilize Spliceostatins

Engineered bacterium produces more stable versions of natural products that show promising anticancer activity

August 25, 2014

Sulfate Click Chemistry

Researchers use SO2F groups as new links in simple selective reactions for forming carbon-heteroatom bonds

August 20, 2014

Peptide-Drug Conjugate Kills Persistent Bacterial Cells

Antibiotics: Adding a peptide that penetrates cell membranes to an existing antibiotic allows the drug to enter bacterial sleeper cells that can cause chronic infections

August 18, 2014

Less Radical Stannylation Mechanism Revealed

ACS Meeting News: Alkyne hydrostannylation long believed to proceed solely via a radical pathway appears to involve a cationic vinylstannane intermediate

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