Already have an ACS ID? Log in
Renew your membership, and continue to enjoy these benefits.
Already an ACS Member? Log in here
Choose the membership that is right for you. Discount will be applied automatically at checkout.
Enjoy these benefits no matter which membership you pick.
Most Popular in Analytical Chemistry
When you really need a clear squid hatchling, what do you reach for? A system developed by a team of researchers in Vienna may present a compelling option. The team calls it DEpigmEntation-Plus-Clearing, or DEEP-Clear for short, and they say it removes a wide range of naturally occurring biological pigments including pterins, ommochromes, heme, carotenoids, and melanin while remaining compatible with several staining and fluorescence-labeling techniques. Here, they’ve cleared a longfin inshore squid, applied an immunohistochemistry label to its nervous system, and captured this 3-D image using light-sheet microscopy, which captures a series of 2-D images and then stacks them into a 3-D model. The researchers say DEEP-Clear will help scientists study the intricate connectivity of difficult systems in intact organisms.
Credit: Science Advances 2020, DOI: 10.1126/sciadv.aba0365
Do science. Take pictures. Win money. Enter our photo contest here.
This article has been sent to the following recipient: