Issue Date: August 29, 2005
Placebos activate endorphins
People often feel better when they believe they have taken a painkiller—even if its a placebo. Now, researchers at the University of Michigan and the University of Maryland have shown that the placebo effect is not merely psychological and that it has a physiological basis (J. Neurosci. 2005, 25, 7754). Michigans Jon-Kar Zubieta and colleagues injected saline solution into the jaw muscles of male volunteers to cause pain. As the experiment proceeded, additional solution . . .
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