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Web Date: October 19, 2006

Strawberry Flavonoid Enhances Memory

Mouse study shows that small molecule mimics peptides to help nerve cells
Department: Science & Technology

Neurotrophic factors are polypeptides that promote the well-being of nerve cells, but their clinical use for, say, sustaining memory, is limited because the compounds have trouble getting past the blood-brain barrier. Pamela Maher of the Salk Institute for Biological Studies in La Jolla, Calif., and colleagues have now identified the flavonoid fisetin as a small molecule that has several properties of a neurotrophic factor and can be taken orally (Proc. Natl. Acad. Sci. . . .

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