Issue Date: December 17, 2007
RNA Transcription's Newfound Complexity
Expression of specific genes is controlled by the complex pattern of phosphorylation of the enzyme that converts DNA into RNA, according to a report by Dirk Eick of the Munich Center for Integrated Protein Science, Shona Murphy of the University of Oxford, and colleagues in Science (2007, 318, 1777 and 1780). The enzyme, RNA polymerase II, is attached via an "umbilical cord" to proteins that help process the RNA product. This flexible tether, . . .
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