Issue Date: June 16, 2008
Visualizing A Protein's Shape-Shifting
By using an advanced NMR technique, researchers in Germany have taken a closer look at how a protein can alter its structure to bind to different partners (Science 2008, 320, 1471). In the past, it had been difficult to determine the molecular mechanism underlying these conformational changes because researchers had trouble observing protein motions at the right time scales. Now, Christian Griesinger and Bert L. de Groot of the Max Planck Institute for . . .
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