Volume 86 Issue 45 | p. 37 | Concentrates
Issue Date: November 10, 2008

Bacteria Trigger Blood Coagulation

Under the right conditions, bacteria can cause blood coagulation during infections, rather than the body???s immune response as believed
Department: Science & Technology

Bacterial infections in blood are often accompanied by blood coagulation, but this phenomenon has been believed to result from immune and inflammatory responses. Rustem F. Ismagilov of the University of Chicago and coworkers now show that the bacteria themselves can trigger coagulation under the right circumstances (Nat. Chem. Biol., DOI: 10.1038/nchembio.124). The researchers found that activation of blood coagulation depends on the clustering of bacterial cells rather than on the total amount of bacteria . . .

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