Volume 86 Issue 6 | pp. 53-54
Issue Date: February 11, 2008

Flu Virus Proton Channel Analyzed

Structures of key surface protein suggest different drug mechanisms
Department: Science & Technology

TWO RESEARCH GROUPS have independently used different methods to obtain long-sought structures of M2, a key ion-channel protein on the surface of influenza virus. The work could help scientists figure out why the virus has recently become resistant to two of the four drugs approved as antiflu agents. It could also lead to the design of more-effective medications.

But scientists will first have to better understand the implications of the new findings. The two studies . . .

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