Volume 87 Issue 33 | p. 38 | Concentrates
Issue Date: August 17, 2009

Clathrin Smuggles Quantum Dots Into Living Cells

A neuropeptide helps slip CdSe-ZnS quantum dots through cell membranes by recruiting clathrin, a protein that facilitates endocytosis
Department: Science & Technology
News Channels: Nano SCENE
Keywords: clathrin, quantum dot, nanoparticle, endocytosis

Peptide coatings can help nanoparticles slip into cells, a process that may prove useful for in vivo imaging or drug delivery if scientists can clear up how it works. Now, Abdulaziz Anas, Mitsuru Ishikawa, Vasudevanpillai Biju, and coworkers with Japan’s National Institute of Advanced Industrial Science & Technology have a better idea after thoroughly studying the insect neuropeptide allatostatin and learning that it helps CdSe-ZnS quantum dots pass through cell membranes by recruiting clathrin, . . .

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