Volume 87 Issue 37 | p. 28 | Concentrates
Issue Date: September 14, 2009

Killing TB In Its Sleep

An antiparasitic drug can kill tuberculosis bacteria, whether they’re actively replicating or not, hinting at a possible new treatment
Department: Science & Technology
Keywords: tuberculosis, antibiotics, metabolism, parasites

A drug already approved by FDA for treating diseases caused by parasitic protozoans such as Giardia lamblia is also effective against cultures of the bacterium that causes tuberculosis, according to a study in the Journal of Medicinal Chemistry (DOI: 10.1021/jm9010719). The agent, nitazoxanide, could be a good starting point for designing new TB drugs. Eradicating TB with established drugs takes months or years, . . .

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