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Web Date: April 1, 2009

Brain Hormone Has Role In Addiction

Blocking hormone receptor could curtail cocaine craving
Department: Science & Technology

New findings about a peptide produced in the brain might lead to a novel pathway for treating drug addiction.

The peptide is melanin-concentrating hormone (MCH), a natural appetite stimulant. A large amount of the hormone's receptor, MCH1R, is found in a brain region that helps control behaviors associated with reward and motivation. So Olivier Civelli of the University of California, Irvine, reasoned that MCH and its receptor might participate in addiction.

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Chemical & Engineering News
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