Volume 88 Issue 24 | p. 39 | Concentrates
Issue Date: June 14, 2010

Key Anti-HIV Antibody Analyzed

Structure revives hopes for an effective AIDS vaccine
Department: Science & Technology
Keywords: AIDS, HIV, PG16, antibody, vaccine

Two teams have structurally analyzed an antibody with unusually potent and broad activity against HIV strains, reviving hopes for an effective vaccine, which is urgently needed to fight AIDS. Last year, researchers discovered two antibodies that neutralize 70 to 85% of global HIV strains and have much greater potency than previous anti-HIV antibodies. The crystal structure of one of the antibodies, PG16, has now been determined independently by groups led by Dennis R. . . .

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