Volume 88 Issue 30 | p. 4 | Letters
Issue Date: July 26, 2010

Another Take On Platinum Cancer Drugs

Department: Letters

The recent article “Platinum Drugs Take Their Toll” summarized the lack of success in bringing new platinum anticancer drugs to the clinic (C&EN, June 28, page 24). Although the process to advance or terminate a new drug candidate is quite complex, a few points concerning drug discovery in the platinum world are worth noting.

Forty years ago, Professor Barnett Rosenberg, the discoverer of the anticancer properties of cisplatin, roughly outlined the structure-activity relationships . . .

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