Volume 88 Issue 38 | p. 24 | Concentrates
Issue Date: September 20, 2010

Modified Luciferin Boosts Light Emission

Replacing a functional group in the firefly molecule pumps up the luminescence intensity
Department: Science & Technology
News Channels: JACS In C&EN
Keywords: luciferin, Ultra-Glo, bioluminescence, firefly

By replacing a functional group in the firefly molecule luciferin, researchers have pumped up the intensity of light emitted by the luminescent molecule (J. Am. Chem. Soc., DOI: 10.1021/ja104525m). Fireflies light up the night, thanks to the luciferase-catalyzed reaction of oxygen and adenosine-5ʹ-triphosphate with D-luciferin to form an excited-state oxyluciferin molecule. When this molecule relaxes to its ground state, it gives off the . . .

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