Volume 88 Issue 9 | p. 12 | News of The Week
Issue Date: February 25, 2010

A Protein That Aids Forgetting

Neuroscience: Small G-protein Rac helps the fruit fly brain remove memories
Department: Science & Technology
Keywords: memory, neuroscience, Rac

The act of forgetting is essential for clearing space in the brain for new information, yet the biochemistry underlying this process has never been ascertained. Now, Yi Zhong, a neuroscientist at Cold Spring Harbor Laboratory, in New York, and coworkers have for the first time identified a molecule that the brain uses to erase short-term memory (Cell 2010, 140, 579).

The molecular eraser is Rac, a small G-protein previously known for its participation . . .

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