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Web Date: November 9, 2010

A New Alternative To FRET

Bioanalysis: Surface energy transfer works over larger distances than does the more-established fluorescence technique
Department: Science & Technology
News Channels: JACS In C&EN, Analytical SCENE
Keywords: nanoparticle, energy transfer, membrane, protein, FRET

A team of scientists in Florida and China have found a longer molecular ruler. They have demonstrated that an optical technique called surface energy transfer (SET) can increase the distances that scientists can measure within or between proteins in a live cell (J. Am. Chem. Soc., DOI 10.1021/ja106360v).

Fluorescence resonance energy transfer (FRET) is the dominant optical technique to . . .

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