Volume 89 Issue 12 | p. 42
Issue Date: March 21, 2011

Magnetic Field Triggers Liposome Release

Confocal laser scanning microscopy used to spy on lipid vesicles as they release their payload in a low-frequency magnetic field
Department: Science & Technology
Keywords: drug delivery, magnetic liposomes, magnetic nanoparticles, lipid vesicles

Using confocal laser scanning microscopy, researchers in Europe have determined the release mechanism of a small fluorescent molecule from a lipid vesicle in a low-frequency magnetic field (J. Phys. Chem. Lett., DOI: 10.1021/jz2000936). Because they are biocompatible and can carry a variety of compounds, lipid vesicles are promising drug delivery vehicles. By adding magnetic nanoparticles to the vesicles’ lipid bilayers, scientists can induce liposomes to discharge their small-molecule payloads with an applied alternating . . .

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