Volume 89 Issue 31 | p. 37 | Concentrates
Issue Date: August 1, 2011

Fluorescent Labels Color Code RNA

Department: Science & Technology
News Channels: Analytical SCENE
Keywords: RNA, aptamer, fluorophore, fluorescence, GFP

Researchers now have a way to genetically encode fluorescent labels for monitoring selected RNAs. Genetically encoded labels were previously available only for proteins, through incorporation of fluorescent proteins such as green fluorescent protein (GFP). Jeremy S. Paige, Karen Y. Wu, and Samie R. Jaffrey of Cornell University’s Weill Medical College developed RNA sequences known as aptamers that bind fluorophores similar to those found in the fluorescent proteins (Science, DOI: 10.1126/science.1207339). The fluorophores don’t . . .

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