Issue Date: August 29, 2011
Prefab Synthesis Moves Ahead
Two studies report the first isolation of α-boryl aldehydes, bifunctional reagents that facilitate synthesis of organic compounds that were previously difficult or impossible to make. The work could enable nonexperts in synthesis to rapidly compose complex organic molecules from simple building blocks in an automated manner—similar to the way peptides are made today.
α-Boryl aldehydes are usually extremely unstable, but newly discovered stable ones are now stored in bottles in Andrei K. Yudin’s lab . . .
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